Shape-dependent global deformation modes of large protein structures
نویسندگان
چکیده
منابع مشابه
Shape-Dependent Global Deformation Modes of Large Protein Structures.
Conformational changes are central to the functioning of pore-forming proteins that open and close their molecular gates in response to external stimuli such as pH, ionic strength, membrane voltage or ligand binding. Normal mode analysis (NMA) is used to identify and characterize the slowest motions in the gA, KcsA, ClC-ec1, LacY and LeuT(Aa) proteins at the onset of gating. Global deformation ...
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ژورنال
عنوان ژورنال: Journal of Molecular Structure
سال: 2010
ISSN: 0022-2860
DOI: 10.1016/j.molstruc.2010.01.009